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About Sequencing & Genomics


An organism's genome refers to all the hereditary information encoded in its genes. Sequencing a complete genome, a gene, or a fragment of genetic material involves determining the order of its sub-units: adenine, cytosine, guanine, and thymine.

Scientists are using individuals' genetic sequences to map and catalog human genetic variation in order to improve understanding of human biology, disease susceptibility, and drug response. As costs falls rapidly, the scale and speed of gene sequencing is increasing. The Human Genome Project required thirteen years and $3 billion to sequence the first complete, general human genome. Subsequent projects, such as the International HapMap Project, examined genetic variation between population groups, raising concerns of giving undue biological significance to social categories of race.

Now, the sequencing of complete genomes of specific individuals is becoming almost routine. For example, the Personal Genome Project plans to sequence 100,000 genomes.

Lower prices have also opened the door to companies that offer personal, direct-to-consumer genetic tests.


The Great Gene Hunt (cont'd)by Pete ShanksBiopolitical TimesSeptember 3rd, 2010Accurate reporting and headlines should not be noteworthy, but when it comes to genetics they are -- and Reuters got one right.
The Tempest: Following the Storm of Reactions after the GAO Reportby Jillian TheilBiopolitical TimesSeptember 1st, 2010The GAO report kicks up a flurry of reactions, from applause to pushback.
Kids swap DNA for fairground rides[Quotes CGS's Marcy Darnovsky]by Ewen CallawayNature NewsSeptember 1st, 2010Researchers' efforts to collect samples at a fair raise ethical questions.
What Should You Ask Before You Give Up DNA? (At a State Fair or Elsewhere)[Quotes CGS's Marcy Darnovsky]by Katherine HobsonWall Street Journal Health BlogAugust 30th, 2010There are a range of concerns you should consider before giving up your DNA
The genetic mystique of ‘me’ medicine [Opinion]by Donna DickensonThe Globe and MailAugust 28th, 2010Are we simply our genes? Is that why we’re unique? Guess again
DNA test flip-flop stirs debate at UC[Quotes CGS's Marcy Darnovsky]by Victoria ColliverSan Francisco Chronicle August 28th, 2010Changes in "Send Your Genes to Cal" program provoke further discussion.
DNA booth: a new fair favorite?[Quotes CGS's Doug Pet]by Jeremy OlsonThe Star TribuneAugust 27th, 2010A University of Minnesota research booth proves popular on the fair's first day.
Class Cancelled: Media Coverage of UC Berkeley’s Retreat on Gene Testsby Jillian TheilBiopolitical TimesAugust 26th, 2010Two weeks after UC Berkeley backed away from its widely criticized “Bring Your Genes to Cal” program, controversy continues.
Marin Voice: Student guinea pigs at Cal?[Quotes CGS's Jesse Reynolds and Marcy Darnovsky] [Opinion]by Alan MillerThe Marin Independent JournalAugust 23rd, 2010The best of plans do often go astray. Data from this study could be good for the university, but not end up serving the best interests of the students.
Wider Debate Swirls Over Ruling That Curtailed Berkeley's DNA Programby Josh KellerThe Chronicle of Higher EducationAugust 19th, 2010Some researchers fear that the health department's position on the Berkeley project could have broader implications for academic research in California
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