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Green's surprising turn on stem cells

Posted by Jesse Reynolds on November 12th, 2008


Ronald Green

In today's Washington Post, libertarian bioethicist Ronald Green issues his recommendation for a "stem cell solution" - a fix that's close to what the incoming Obama administration is likely to adopt. Green calls for opening federal funds for work with stem cell lines derived from embryos created but not needed in fertility treatments. In fact, he takes the surprising  position of limiting this funding to the lines created before the enactment of the revised policy, just like Bush did in 2001:

Like President Bush, President Obama could limit federal research to embryos created for reproductive purposes and abandoned before the statement of his policy. There are more than enough of these embryos to create all the lines we need for research. Under such a policy, there would be no use of embryos created with the intent of stem cell research....

[B]y observing that this policy represented only an extension of the one established by his predecessor, and by stressing the beneficial use of embryos that would otherwise be destroyed, President Obama could succeed in reducing the most vehement opposition to a manageable level.

This is unexpected, considering Green's track record of taking extremely permissive positions. By serving on the ethics advisory board of Advanced Cell Technology, he helped pave the way for cloning-based stem cell research, and opposed limits on payments for women's eggs that are needed for this speculative and unsuccessful line of work. Green has also advocated for inheritable genetic modification for height, weight, and intelligence in order to accelerate the economy and to better match children's outcomes with parents' high expectations.

Does Green's new found moderation represent a change in his perspective, or a shift to accommodate the changed political landscape, or something else? That remains to be seen.

Previously on Biopolitical Times:





Is Singapore pushing the payment boundary?

Posted by Jesse Reynolds on November 11th, 2008


A headline out of Singapore last week stated, "OK To Compensate Egg Donors," coming just a few days after one that warned, "Kidney law to change." In both stories, the Ministry of Health is considering permitting some financial compensation to donors of eggs for research and of kidneys, respectively. And in both cases, the Ministry asserts that the amounts of compensation will not be large enough to act as an inducement.

The Ministry is treading a thin line here. International and national prohibitions on organ sales are well established as being exploitative and coercive, despite black markets and a recent push for opening the market (1, 2, 3 [PDF]). The logic behind eggs is similar, but less ingrained in policy. Selling them for any purpose, for example, is perfectly legal in most of the United States.

The report regarding eggs from the Ministry's Bioethics Advisory Committee is clear: The extraction of eggs poses real health risks, including potential death. The commercialization of eggs is wrong and to be avoided. In fact, the Committee rejects "egg sharing" arrangements, in which a woman undergoing assisted fertility treatment provides some of her eggs for research in exchange for a discount, such as those in the UK as amounting to payment.

Whereas existing Singapore policy allows reimbursement for direct expenses, the new proposal would permit compensation for lost wages and time. The former is consistent with a policy that the altruistic egg provider should be "no better off, nor any worse off." But paying for time is another matter. Isn't this equivalent as hiring someone? And how are payments for time to be calculated so that they are not inducements for, say, the unemployed?

A year ago, I would have worried that, by lowering the bar, this proposed policy would have put pressure on other jurisdictions to join in a race to the bottom. But with the continued lack of success of cloning-based stem cell research, which would use the eggs, and the frequent strides in the alternative methods of cellular reprogramming, I am skeptical if others would bother fighting for such a policy.

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Kids of sperm donor dads ask Canadian court to stop destruction of records

Posted by Marcy Darnovsky on November 7th, 2008


The daughter of an anonymous sperm donor has filed a class action suit in British Columbia to prevent doctors from shredding medical records that contain the identity of her biological father.

Lawyers for Olivia Pratten say it's discriminatory to prevent children conceived with third-party gametes from obtaining the identities and medical histories of their biological parents. Currently, British Columbia law allows fertility doctors to destroy all information about gamete donors after six years.

The lawsuit - the first of its kind in Canada - is based on the guarantees of equality and security of the person in the Canadian Charter of Rights and Freedoms. It's been covered by most Canadian newspapers [1, 2, 3], but has gone unmentioned in the U.S.

Pratten, who is now 26 years old, commented, "Farmers have kept better records on the artificial insemination of cattle than the physicians in BC have kept on people like myself."

The Adoption Council of Canada's vice president, Wendy Rowney, argued that "every Canadian adult has the right to truthful information about his or her origins…It does not matter whether we are adopted or conceived by gamete donation; we all have the right to this information."

The UK's Human Fertility and Embryology Authority (HFEA) ruled donor anonymity impermissible in 2005. Critics of the policy claim the change has caused sperm shortages, but the HFEA says this is not the case.

Donor anonymity is the norm in the United States, but has become controversial in Canada and the UK. In recent years, "donor offspring" have begun forming organizations, setting up registries, and publicizing their case.

This has the looks of a debate coming soon to the U.S., the Wild West of reproductive technologies.

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Sarah Palin, Down syndrome, and the abortion debate

Posted by Marcy Darnovsky on November 7th, 2008


Here’s something for which we may want to thank Sarah Palin: sparking fruitful new contributions to the difficult discussions between advocates of reproductive rights and disability rights.

Many disability rights advocates are pro-choice, but horrified at the almost automatic choices so often made to terminate a pregnancy when a fetus with Down syndrome is identified. Many reproductive rights advocates consider themselves supporters of people with disabilities, but are reluctant to open the door to any questions about women’s motives for abortion.

But two commentaries published this week, both by women whose children have Down syndrome, paint the picture differently. In the Washington Post, Tierney Temple Fairchild, a Charlottesville education and management consultant, writes:

I had a choice, and I chose life. Does that make me pro-choice or pro-life? Our political parties tell us we can't have it both ways….Ten years ago, I made a decision to continue a pregnancy that would lead to a child born with Down syndrome….Ten years after my own choice, I find it disheartening that termination statistics may remain the same, that so many potential mothers choose not to follow Sarah Palin’s example.
And in the Canadian Medical Association Journal, an essay by Renate Lindeman, a spokesperson for Down Syndrome Belongs in Nova Scotia, opens “Take Down syndrome out of the abortion debate” with this:

Trig Palin, the 5-month-old son of vice presidential candidate Sarah Palin, has drawn enormous public notice to Down syndrome. For that, many in the US and Canadian Down syndrome communities are grateful.
But as the mother of 2 children with Down syndrome, it makes me very nervous. I'm not willing to see my kids used as poster children for the anti-abortion movement.

Rather, I see the attention that Sarah and Trig Palin are bringing Down syndrome as an opportunity to take the issue of prenatal screening out of the abortion debate once and for all.




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